Wednesday, 6 August 2008

Impotence drugs help treat brain tumours

Impotence drugs may help carry cancer-fighting drugs through the brain to treat malignant tumours, U.S. researchers reported on Monday.

Tests in rats showed two erectile dysfunction drugs -- Schering-Plough's Levitra and Pfizer's Viagra -- helped carry a chemotherapy drug past the blood-brain barrier, the team at Cedars-Sinai Medical Centre in Los Angeles said.

Rats with brain tumours lived 42 days when injected with the cancer drug adriamycin. But when they also got Levitra, known generically as vardenafil, the rats survived an average of 53 days. Levitra appeared to be more effective, the researchers reported in the journal Brain Research.

Levitra and Viagra, known generically as sildenafil, are in a class of drugs known as PDE5 inhibitors. They were originally tested as heart drugs because they increase blood flow in small vessels.

Complete Article: Reuters UK


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